Risk Factor Differences for Aortic Versus Coronary Calcified Atherosclerosis

Risk factor differences for aortic versus coronary calcified atherosclerosis: the multiethnic study of atherosclerosis.

OBJECTIVE The goal of this study was to compare and contrast coronary artery calcium (CAC) with abdominal aortic calcium (AAC) in terms of their associations with traditional and novel cardiovascular disease (CVD) risk factors. METHODS AND RESULTS We measured both AAC and CAC using computed tomography scans in 1974 men and women aged 45 to 84 years from a multiethnic cohort. Traditional and n...

Risk factor differences in calcified and noncalcified aortic plaque: the Framingham Heart Study.

OBJECTIVE The objective of this study was to determine the prevalence and risk factor (RF) correlates of aortic plaque (AP) detected by cardiovascular magnetic resonance (CMR), which mainly shows noncalcified plaques, and by noncontrast computed tomography (CT), which best depicts calcified plaques, in community-dwelling adults. APPROACH AND RESULTS A total of 1016 Framingham Heart Study Offs...

Patterns and risk factors for systemic calcified atherosclerosis.

OBJECTIVE Complex atherosclerotic lesions contain radio-opaque calcium hydroxyapatite deposits with the degree of calcification correlating with the extent of atherosclerosis. In this study, we aim to determine the patterns of systemic atherosclerotic calcification. METHODS AND RESULTS Whole-body electron beam computed tomography scans were performed on 650 asymptomatic subjects to assess the...

Aortic Valve Replacement for Calcified Aortic Valves

Measuring the effect of risk factors on coronary atherosclerosis: coronary calcium score versus angiographic disease severity.

OBJECTIVES This study sought to determine whether noninvasive quantification of coronary calcium is comparable to selective coronary angiography in measuring the effect of cardiovascular risk factors on coronary atherosclerosis. BACKGROUND Electron beam computed tomography (EBCT) allows the delineation of anatomic coronary atherosclerotic disease and may be useful for noninvasively defining t...